After upgrade to CiviCRM 5.10.3 (Drupal 7, php 5.64) I can do AJAX edits like view and edit address, but if I edit a contact and save them normally, I get Fatal error: Uncaught CRM_Core_Exception: [0: Transaction integrity error: Expected to find active frame thrown in .../sites/all/modules/civicrm/Civi/Core/Transaction/Manager.php on line 107
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If this is still an issue, turn on backtraces (Administer >> System Settings >> Debugging and Error Handling) and repeat the action that causes the error. You can edit the question to include the backtrace, which assists in troubleshooting. – Jon G - Megaphone Tech Apr 20 '19 at 12:44
CiviCRM 5.10.3 is not compatibile with so old PHP 5.64. Maybe here is a problem, look at requirements:
https://docs.civicrm.org/sysadmin/en/latest/requirements/#php
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Actually it states it is compatible: compatible but not recommended due to to PHP end-of life in Dec 2018 – TimETown Mar 22 '19 at 13:51
