They're disabled because you haven't completed all the required actions yet.
Have you remembered to include the the mandatory address and opt-out tokens in the body of your email?
You need to include:
{domain.address}
And at least one of the following:
{action.optOutUrl}
{action.unsubscribeUrl}
The other thing to check is that you have a mailing list selected. It's silly but CiviMail requires one even when you're just sending a test to a single email, so it's worth having a generic 'test' mailing list set up for this purpose (that you can then replace with the 'real' mailing list before you send).